Echinacea Versus Placebo Effect in Common Cold
This study is currently recruiting patients.
Verified by National Center for Complementary and Alternative Medicine (NCCAM) September 2006
Purpose
The design and interpretation of randomized trials is intimately connected to the use of “placebo”. The nature and magnitude of placebo effects, however, is very poorly understood. This study will assess and compare placebo effects and physician interaction effects within a community-acquired common cold model. The goal of this study is to assess two kinds of placebo affects and how physician interaction effects;
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The effect of receiving blinded placebo, compared to no treatment; and
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The effect of receiving open-label active Echinacea treatment compared to blinded active treatment.
| Condition |
Intervention |
Phase |
Common Cold
|
Drug: Echinacea
|
Phase III
|
MedlinePlus
related topics:
Common Cold
Study Type: Interventional
Study Design: Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Efficacy Study
Official Title: The Placebo Effect in Clinical Practice
Further study details as provided by National Center for Complementary and Alternative Medicine (NCCAM):
Expected Total Enrollment: 800
Study start: September 2003; Expected completion: December 2006
As per Brief Summary
Eligibility
Ages Eligible for Study: 12 Years and above, Genders Eligible for Study: Both
Criteria
Inclusion criteria:
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Suspected or known cold
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At least one of the following cold symptoms:
nasal discharge, nasal congestion, sneezing, or sore throat
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Enrolled in school, for children 12 to 17 years of age
Exclusion criteria:
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Pregnancy;
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Symptom duration > 36 hrs
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Concurrent use of antibiotics, antivirals, nasal steroids, decongestants or antihistamines;
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Anticipated need for symptom-relieving meds during cold
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Autoimmune/deficiency disease
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History of allergic rhinitis with current eye itching/sneezing
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History of asthma w/current cough/SOB
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Prior study entry
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Allergy to Echinacea
Location and Contact Information
Please refer to this study by ClinicalTrials.gov identifier NCT00065715
Wisconsin
University of Wisconsin-Madison Department of Family Medicine, Madison, Wisconsin, 53706-1490, United States; Recruiting
Study chairs or principal investigators
Bruce Barrett, MD PhD, Principal Investigator, University of Wisconsin-Madison
More Information
http://www.fammed.wisc.edu
Study ID Numbers: R01 AT001428; BarrettB
Last Updated: September 14, 2006
Record first received: July 31, 2003
ClinicalTrials.gov Identifier:
NCT00065715
Health Authority: United States: Federal Government
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