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Clinical Trial Studies
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Last Updated: Jul 21, 2011 - 12:58:55 PM

Women-Focused HIV Prevention in the Western Cape, recruiting participants.


By Clinical Trials


Dec 10, 2008 - 1:03:03 PM


 

 

 

Women-Focused HIV Prevention in the Western Cape

This study is currently recruiting participants.
Verified by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), October 2008

Sponsors and Collaborators: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Medical Research Council, South Africa
Information provided by: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
ClinicalTrials.gov Identifier: NCT00729391

 

Detailed Description:

Surveillance data indicate that HIV risk and substance use is a serious problem among South African women. This study, funded by the National Institute on Child Health and Human Development (NICHD), builds on findings from a recently completed pilot study among women in less affluent townships and communities in the Western Cape (Wechsberg et al., 2008). The pilot study tested the effectiveness of an evidence-based woman-focused intervention in reducing drug use, sexual risk, and victimization by addressing the intersection of these factors among 100 poor, substance-using women of colour.

The primary aim of this study is to test the effectiveness, through a randomized controlled trial (RCT), of VCT plus a woman-focused intervention relative to VCT only to increase knowledge and skills to reduce substance abuse, sexual risk, and victimization, and to an equal-attention (nutrition) control group at 3-, 6-, 9-, and 12-month follow-ups. A secondary aim is to examine the moderating effect of victimization (i.e., sexual and physical) and the mediating effects of HIV risk knowledge, condom use skills, sexual negotiation assertiveness, and relationship power on the effectiveness of the woman-focused groups to decrease risk related to drug use, sexual risk, and sex-related-victimization relative to the rapid testing group and to the equal-attention control group.

  Eligibility
Ages Eligible for Study:   18 Years to 33 Years
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   No

Criteria

Inclusion Criteria:

  • To be eligible for the study, participants must be: (a) female; (b) report use of at least two drugs—alcohol, marijuana, methamphetamine (tik), Mandrax (methaqualone), cocaine (crack and/or powder), heroin (Thai White), glue, MDMA (ecstasy), or LSD—at least once a week in the past 90 days; (c) be sexually active within the past 30 days; (d) be aged 18 to 33 years; (e) live in the communities around the airport; and (f) provide verbal consent to be screened for eligibility and written consent to participate in the study.

Exclusion Criteria:

  • If participants do not meet all of the inclusion criteria, they will be excluded from the study.
  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00729391

Contacts
Contact: Wendee M Wechsberg, PhD     919-541-6422     wmw@rti.org    
Contact: Bronwyn J Myers, PhD     27-21-938-0218     Bronwyn.Myers@mrc.ac.za    

Locations
South Africa
Recruiting
      Cape Town, South Africa
      Contact: Wendee M Wechsberg, PhD     919-541-6422     wmw@rti.org    
      Contact: Bronwyn J Myers, PhD     27-21-938-0218     Bronwyn.Myers@mrc.ac.za    
      Sub-Investigator: Bronwyn Myers, PhD            

Sponsors and Collaborators

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